Searchable abstracts of presentations at key conferences in endocrinology

ea0056gp225 | Thyroid Cancer - Diagnostics & Treatments | ECE2018

Germline mutations in KIF1B gene in two families with familial non-medullary thyroid cancer (FNMTC)

Anon Aida Orois , Porta Mireia Mora , Rabinovich Irene Halperin , Gara Sudheer Kumar , Kebebew Electron , Ambros Josep Oriola

Introduction: Familial non-medullary thyroid cancer(FNMTC) represents 3–9% of thyroid cancer cases. Although the susceptibility genes for syndromic FNMTC are known, most cases of FNMTC are nonsyndromic and the genetic causes are unknown.Patients and methods: We conducted a multicenter study to identify a candidate susceptibility gene for nonsyndromic FNTMC. We collected blood specimens, clinical and pathological data from 38 kindreds with FNMTC (32 ...